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GN 721 Genetic Data Analysis
The course aims to provide students with the relevant background knowledge and quantitative skills for conducting genetic data analysis to evaluate the genetic effects of complex traits. The course will focus on statistical methodologies and analytical strategies for population-based association studies with genotype and sequencing data collected from whole genome and exome. The specific topics include genetic variants; genetic identity coefficients and its applications; heritability; Hardy-Weinberg disequilibrium; recombination; linkage disequilibrium and association mapping; genome-wide association studies (GWAS); population substructures; multiple testing; single-variant and multi-variant association methods; next-generation sequencing (NGS) data and rare variant analysis; copy number variant analysis; analysis using summary statistics.
Prerequisite: 厂罢听511 or equivalent
Typically offered in Fall only
This course is offered alternate years
Genetics and Genomics (MR)
/graduate/interdisciplinary/genetics-genomics/genetics-genomics-mr/
1 Students can also take a more advanced statistics course, such as聽 ST聽512 Statistical Methods For Researchers II 2 Other courses that do not appear on this list may be counted with the approval of the DGP.聽 This course may not be a statistics or data science class that is not focused heavily on Genetics and/or Genomics data.聽 Examples of potential courses are:聽 BIO聽562 Fundamentals of Bioinformatics ,聽 BIT聽815 Advanced Special Topics 聽(Deep Sequencing Analysis,聽 GGS聽771 Data Science for Genetics & Genomics ,聽 GN聽756 Computational Molecular Evolution ,聽 GN聽757 Quantitative Genetics Theory and Methods ,聽 ST聽590 Special Topics 聽(Bioinformatics II),聽 厂罢听721 / GN聽721 Genetic Data Analysis 3 Other courses that do not appear on this list may be counted with the approval of the DGP. Examples of potential courses are:聽 GGS聽840 Professional Development & Ethics in Genetics & Genomics , GES 5** Genetic Engineering and Society,聽 PHI聽816 Introduction to Research Ethics ,聽 TOX聽820 Special Problems In Toxicology 4 Students will work with their advisor to select Advised Electives appropriate for their academic and professional goals. At most 3 credits of research may be used in the Advised Elective category.
Genetics and Genomics (MS)
/graduate/interdisciplinary/genetics-genomics/genetics-genomics-ms/
1 Students can also take a more advanced statistics course, such as聽 ST聽512 Statistical Methods For Researchers II 2 Other courses that do not appear on this list may be counted with the approval of the DGP.聽 This course may not be a statistics or data science class that is not focused heavily on Genetics and/or Genomics data.聽 Examples of potential courses are:聽 BIO聽562 Fundamentals of Bioinformatics ,聽 BIT聽815 Advanced Special Topics 聽(Deep Sequencing Analysis,聽 GGS聽771 Data Science for Genetics & Genomics ,聽 GN聽756 Computational Molecular Evolution ,聽 GN聽757 Quantitative Genetics Theory and Methods ,聽 ST聽590 Special Topics 聽(Bioinformatics II),聽 厂罢听721 / GN聽721 Genetic Data Analysis 3 Other courses that do not appear on this list may be counted with the approval of the DGP. Examples of potential courses are:聽 GGS聽840 Professional Development & Ethics in Genetics & Genomics , GES 5** Genetic Engineering and Society,聽 PHI聽816 Introduction to Research Ethics ,聽 TOX聽820 Special Problems In Toxicology 4 Students will work with their advisor to select Advised Electives appropriate for their academic and professional goals. At most 3 credits of research may be used in the Advised Elective category.
Genetics and Genomics (PhD)
/graduate/interdisciplinary/genetics-genomics/genetics-genomics-phd/
1 Students can also take a more advanced statistics course, such as聽 ST聽512 Statistical Methods For Researchers II 2 Other courses that do not appear on this list may be counted with the approval of the DGP.聽 This course may not be a statistics or data science class that is not focused heavily on Genetics and/or Genomics data.聽 Examples of potential courses are:聽 BIO聽562 Fundamentals of Bioinformatics ,聽 BIT聽815 Advanced Special Topics 聽(Deep Sequencing Analysis,聽 GGS聽771 Data Science for Genetics & Genomics ,聽 GN聽756 Computational Molecular Evolution ,聽 GN聽757 Quantitative Genetics Theory and Methods ,聽 ST聽590 Special Topics 聽(Bioinformatics II),聽 厂罢听721 / GN聽721 Genetic Data Analysis 3 Other courses that do not appear on this list may be counted with the approval of the DGP. Examples of potential courses are:聽 GGS聽840 Professional Development & Ethics in Genetics & Genomics , GES 5** Genetic Engineering and Society,聽 PHI聽816 Introduction to Research Ethics ,聽 TOX聽820 Special Problems In Toxicology