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TOX 701 Principles and Mechanisms of Molecular and Biochemical Toxicology, I
罢翱齿听701听听Principles and Mechanisms of Molecular and Biochemical Toxicology, I听听(3 credit hours)听听
This course covers the general principles of toxicology including xenobiotic dose response relationships, absorption, distribution, elimination, metabolism, excretion, and pharmacokinetic modeling. The course then focuses on the molecular and biochemical basis of toxicant action, first at the cellular level involving cell injury, necrotic cell death, regulated cell death and pathology and then at the organ level involving acute toxicity in the kidney, lung and liver. The course also covers endocrine disruption, mutagenesis, DNA repair and chronic toxicity involving carcinogenesis and the importance of critical windows of exposure.
Prerequisite: 叠颁贬听451, Graduate standing
Typically offered in Fall only